Dane Darío*
The late 20th century saw the development of various irresistible infections that are brought about by microorganisms that seldom cause illness in typical, sound immunocompetent hosts. The rise of these illnesses shows that the current ideas of pathogenicity and destructiveness don't consider the way that both the microorganism and the host add to microbial pathogenesis. To address this obstacle to investigations of host–microorganism communications, we propose another hypothetical way to deal with understanding microbial pathogenesis, known as the 'harm reaction' structure.