Química orgánica: investigación actual
Acceso abierto

abstracto

Síntesis de cuatro nuevos análogos de brasinoesteroides 11-oxo-funcionalizados en el anillo C, con cadena lateral 24-Nor y que contiene esqueleto de ácido colánico 5β

Luis Espinoza

In this work, I report the synthesis of four new brassinosteroids analogues with 24-nor side chain and 11-oxo functionalized on C ring, containing 5β-cholanic acid skeleton: 3α, 12β-diacetoxy-22(S), 23-dihydroxy-24-nor-5β-cholan- 11-one (20); 3α, 12β, 22(S), 23-tetrahydroxy-24-nor-5β-cholan-11-one (21); 3α, 12β, 22(S), 23-tetraacetoxy-24-nor-5β- cholan-11-one (22) and 3α, 12β-diacetoxy-[2,2-dimethyl-22(S), 23-dioxolane]-24-nor-5β-cholan-11-one (23) derivatives from commercial deoxycholic acid.