Urología médica y quirúrgica

Urología médica y quirúrgica
Acceso abierto

ISSN: 2168-9857

abstracto

Evaluation of Hormonal and Biochemical Risk Factors for Benign Prostatic Hyperplasia: A Possible Way for Management and Prevention of Benign Prostatic Hyperplasia

Chinedum Joseph Ndefo, Parker Elijah Joshua*, Eleazar Chukwuemeka Anorue

Objective: To identify some risk factors that contributes to the development and severity of BPH among the elderly in Enugu state, Nigeria.

Study design: One hundred men aged 53 years-85 years were used for the study; the study was divided into two groups consisting of 50 male patients diagnosed with BPH and 50 healthy subjects.

Methods: Twenty millilitre of whole blood samples were collected from each patient and the following parameters were investigated; oestrogen, testosterone, lipid profile, PSA, PAP, TAP, electrolyte concentration and antioxidant biomarkers.

Results: It was found that increase in PAP, TAP, total cholesterol, TAG, LDL, oestrogen, potassium and sodium and decrease in levels of catalase, GPx, selenium, HDL and testosterone are risk factors for the development and severity of BPH.

Conclusions: In view of this, modifiable lifestyles can be adopted for the prevention, management and treatment of BPH.

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